The course will review the application of biochemical engineering to the development and commercialization of vaccines and biologics.  Vaccines and biologics are much more complex than small molecule drug products and present unique challenges for successful commercialization and impact on human health.  The course will focus on “what, when and where” in the bioproduct development lifecycle that engineering enables and contributes to successful product commercialization. This course will include an overview of vaccines and biologics from historical context, product technologies, process technologies, immunology, clinical and regulatory considerations, economics, ethics, and medical impact on global human health.  The course will utilize case studies to examine what worked well - as what lessons were learned which might be applied for future product development.