This course introduces the fundamentals of cell structure and function, emphasizing the techniques and technologies available for the study of cell and molecular biology. A problem-based approach with translational implications is used to motivate each topic. The themes are divided into three general sections: 1) cell structure and function, which includes cell chemistry, organelles, enzymes, membranes, membrane transport, the cytoskeleton, intracellular compartments, and adhesion structures; 2) energy flow in cells, which concentrates on the pathways of glycolysis and aerobic respiration; 3) information flow in cells, which focuses on modern molecular biology and genetic engineering, including DNA replication, the cell cycle, signal transduction, gene expression, gene regulation, and protein synthesis.  Students will work throughout the semester on a team manuscript that will be peer reviewed and evaluated editorially by course instructor and TAs.