Syllabus for Roster(s):
- 17Sp BME 6550-003 (ENGR)
- 17Sp ECE 6502-003 (ENGR)
In the UVaCollab course site: 17SP Inference Methods
Topics
- Review of probability
- Random variables & processes
- Markov chains and Perron-Frobenius theory
- Hidden Markov models
- Inference, estimation, and phylogenetics
- Maximum likelihood
- Hypothesis testing
- Bayesian inference
- Monte-Carlo Markov chains
- Applications to phylogenetics
- Hidden Markov models in computational biology
- Three problems: evaluation, decoding, and inference
- Gapped sequence alignment
- Gene finding
- Protein classification
- Information theory and computational biology:
- Introduction to Information theory
- Source coding and compression of biological sequences
- Stochastic approximation and sequence evolution
- Communication channels and sequence reconstruction
- Constrained codes and models of DNA as language